March 24, 2021

High Content Imaging and Characterization of Circulating Tumor Cells (CTC) from Cancer Patients

March 24, 2021

BRAF V600E Mutation Allele- Specific PCR Assay in Circulating Tumor Cells

March 24, 2021

Simultaneous Quantification of Multiple Signaling Molecules in Individual Circulating Tumor Cells (CTCs) by Multi-Color Laser Scanning Cytometry

March 24, 2021

Biomarker Assay Validation for Intra-Tumoral Quantification of Phosphorylated VEGFR-2

March 24, 2021

Analysis of Heterogeneity of CTCs Isolated by ApoStream® from Blood of Primary Breast Cancer Patients

March 24, 2021

Comparison of Genomic and Proteomic Biomarkers in CTCs and Biopsies from HRPC Patients

March 24, 2021
data sciences

Biomarker Analysis to Inform Dosing Schedule of a MEK1 Inhibitor for Treatment of BRAF-Mutated Melanoma

March 24, 2021

An Analysis of the CK2 Pathway in PBMCs, CTCs, and Plasma in Patients with Solid Tumors

Clinical Application: Pharmacodynamic Assessment of a CK2 Inhibitor Key Words: PBMCs, CTCs, plasma, biomarker expression, pharmacodynamics Background: CK2 protein kinase is a constitutively active enzyme that mediates signaling in multiple pathways including oncogene and cytokine signaling. CK2 is an attractive target for anticancer therapy due to its overexpression in most […]
March 24, 2021

Therapeutic Target Analysis in CTCs Isolated from NSCLC Patients Using ApoStream®

Clinical Application: Identification of folate receptor alpha (FRA) positive CTCs for patient stratification Key Words: CTCs, ApoStream®, patient stratification, protein expression, NSCLC Background: This study was initiated to explore the utility of using biomarker expression levels in CTCs as a means of patient selection for treatment in a clinical trial. […]