Multi-omic data offers unprecedented depth into disease biology, but without integration, it often remains fragmented and difficult to interpret. Precision for Medicine brings structure and strategy to this complexity, helping sponsors connect molecular signals to meaningful clinical outcomes.
Precision medicine often requires derivation of meaningful insights from biological complexity. Multi-omics, the integrated analysis of multiple “omics” datasets, enables this by systematically integrating diverse molecular data, such as genomic, transcriptomic, proteomic, and cellular profiles to construct a comprehensive and clinically relevant understanding of disease biology.
However, sponsors often face challenges integrating these diverse and complex data sets. Each “omic” study is often performed independently, managed by different vendors, each with their own platforms, formats, and timelines. Sponsors must reconcile this fragmentation of data, manage multiple contracts, and navigate mismatched outputs. The effects are slower progress, increased risk and missed opportunities.
Precision for Medicine addresses this challenge by serving as a scientific guide, translating complex, multi-dimensional data into coherent information. Through strategic assay design and careful selection of relevant omics, we ensure that each sample is maximally leveraged, biological variation is accurately characterized, and decisions are informed by a robust analytical framework.
Multi-omics is a strategic lens for understanding biology across interconnected layers. Leveraging high-resolution multiplexing technologies, Precision integrates genomics, epigenomics, transcriptomics, proteomics, spatialomics, cytomics and pathomics into unified workflows that align with therapeutic goals, disease mechanisms, and patient-specific biology.
This integration enables sponsors to investigate patient-specific cases using data from proteins, cells, DNA, RNA, tissue, and clinical metadata. Spatial profiling and digital pathology provide detailed visualization of cellular architecture and molecular interactions within tissue, including immune activity, while transcriptomic and proteomic data reveal gene expression and protein dynamics. Cytomics adds insight into immune cell populations and cytokine environments, critical for understanding therapeutic response.
Through consultation, a sponsor’s initial request for next-generation sequencing may evolve into a more tailored approach like spatial profiling or proteomics, depending on the therapeutic context.
Precision is leading the way in generating high-quality data and advancing analytical capabilities to support personalized treatment strategies. Among emerging approaches is pharmacogenomics, the study of how an individual's genetic makeup influences their response to medications. By integrating pharmacology and genomics, pharmacogenomics enables the development of safer, more effective therapies tailored to each person’s genetic profile.
Biological variability underpins precision medicine. Differences among subjects in genetic makeup, environmental exposures, protein expression, immune response, and clinical history shape how diseases progress and how therapies perform. Precision captures this variability using multi-omic platforms designed to reflect real-world biology. Clinical demographics, treatment history, and disease state are incorporated into study and assay designs, ensuring that data reflects the broad range of patient diversity.
Spectral flow cytometry, for example, enables analysis of 60 plus markers, theoretically, allowing for 3,600 possible combinations of cellular phenotypes (though some would never occur in vivo). AI-enabled/machine learning analysis helps distill these patterns, revealing information that may not be detected using more traditional manual analysis.
This level of granularity supports biomarker discovery and trial optimization, which then allows patient stratification, turning biological variability into an advantage when designing personalized medicines.
Each biospecimen is a strategic asset, but limited tissue access, especially in oncology, can constrain discovery and delay development. To address this challenge, Precision developed ApoStream®, a proprietary platform that captures viable whole cells from liquid biopsies. It preserves cellular morphology and enables downstream multi-omic analysis, providing sponsors with valuable biological perspectives, even when traditional biopsies aren’t feasible.
Once samples are profiled, the challenge shifts to interpreting vast, complex datasets. Here, we utilize and recommend platforms from leading AI-powered pathology companies. In parallel, Real-World Data has become increasingly relevant, supporting biomarker discovery and trial optimization through advanced pattern recognition and data integration.
For example, a collaboration with SOPHiA GENETICS led to the development and validation of a custom CDx module that integrates next-generation sequencing (NGS) data with machine learning, supporting patient enrollment by helping sponsors identify responders, refine trial design, and personalize treatment strategies.
Together, Precision's in-house innovations and partner technologies create a connected workflow from sample to interpretation to help sponsors move faster, reduce error, and make smarter decisions grounded in real biology.
As a science-led global CRO, Precision combines deep biological expertise with integrated lab and trial capabilities. This unified model enables sponsors to move beyond rigid frameworks towards adaptive strategies and align scientific discovery with clinical execution.
Sponsors face increasing pressure to unify fragmented workflows, accelerate timelines, and make confident decisions from complex data. Precision’s integrated approach meets this need by aligning scientific strategy with operational execution. Our centralized biospecimen services, biomarker platforms, and consultative support eliminate vendor silos and unify reporting, reducing delays and ensuring consistent data quality across programs.
We built this model not just for efficiency, but to empower sponsors with the clarity and control that is required from discovery to clinical implementation. By integrating lab and trial capabilities under one scientific umbrella, Precision helps sponsors reduce complexity, speed timelines, and often reduce costs while keeping focused on what matters most: turning life-changing therapies into reality for patients.
Precision has executed more than 650 clinical trials and 2000+ lab programs across oncology, autoimmune disease, rare disease, cell and gene therapies. Our depth in these areas allows for tailored multi-omic strategies that support your unique needs. The following examples illustrate how multi-omic strategies are being applied to real-world clinical challenges to deliver measurable impact across diverse areas.
Early investment in integrated multi-omic strategies improves the efficiency of bringing precision therapies to market. Precision for Medicine meets this need by transforming fragmented data into clear, decision-ready insights through consultative partnerships, advanced platforms, and AI-enabled analysis.
We design strategies that reflect biological variability and align with therapeutic goals, treating each sample as a strategic asset and each generated dataset as a decision-driving tool.