Global Immune Monitoring Solutions

Precision provides an industry-leading array of comprehensive immune monitoring solutions, from the development of customized assays for early clinical studies to managing the logistical and immune monitoring testing needs of global, multi-site studies.

We leverage multiple technology platforms on a global scale, including proprietary innovations developed in-house, like Epiontis ID, which provides immunophenotyping even on non-viable samples. Our expertise also includes analyzing immune status of tumor or tissue biopsies, and liquid biopsy analysis of rare circulating tumor cells.

Global Immune Monitoring Solutions

Precision provides an industry-leading array of comprehensive immune monitoring solutions, from the development of customized assays for early clinical studies to managing the logistical and immune monitoring testing needs of global, multi-site studies.

We leverage multiple technology platforms on a global scale, including proprietary innovations developed in-house, like Epiontis ID, which provides immunophenotyping even on non-viable samples. Our expertise also includes analyzing immune status of tumor or tissue biopsies, and liquid biopsy analysis of rare circulating tumor cells.

Immune Monitoring by Flow Cytometry

Flow cytometry provides high-dimensional insight into immune cells and target engagement. We have both research-grade instruments for up to 20 parameters analysis, and CLIA instruments, all supported by a global sample processing and logistics network to ensure sample integrity.

Immune Monitoring by Epiontis ID

Precision’s proprietary Epiontis ID technology delivers robust, repeatable, yet cost-effective immune cell phenotyping without the need for viable cells. With over 100,000 clinical samples analyzed, Epiontis ID is a globally-accepted immune monitoring technology.

Cytokine Profiling

For an in-depth assessment of inflammatory responses, our cytokine profiling assays are designed to measure cytokines and chemokines released from chosen target cells. We use Luminex, MesoScale Discovery, and Quanterix SIMOA technology for sensitive detection in complex matrices, as well as ELISAs for single analytes.

Gene Expression Profiling of Biopsies

Understand target expression, adaptive and innate immune responses at the gene expression level. Technologies we use for gene expression profiling include NanoString, Illumina RNA-seq, ddPCR, and qPCR.

ELISpot and FluoroSpot

ELISpot and FluoroSpot can quantify antigen-specific T or B cells. In addition to assays, we offer large banks of cryopreserved control cells.

Custom Immune Monitoring Assays

For custom assays, we apply our scientific expertise and engineering excellence to design effective and efficient assays to achieve your project’s specific goals.

To flow or not to flow: immune cell profiling in translational research

Learn about the immune monitoring strengths of both flow cytometry and epigenetic immune profiling, including when each of these technologies can best be utilized in a clinical study.

Efficient sample management logistics enable global immune monitoring services

Precision’s immune monitoring services are strengthened by a global logistics network designed to safeguard sample integrity and maximize data reliability.
Global sample processing
  • Global PBMC processing in 24-hours or less
  • Regular competency assessment and monitoring to ensure site-to-site and lab-to-lab data comparability
  • Long- and short-term storage at optimal temperatures
Controlled biostorage

Our 100,000 sq. ft. primary biorepository was the first to receive CAP certification and currently stores >20 million biospecimens under controlled conditions. We can store any type of fluid or solid biological specimen at controlled ambient temperatures, +4℃, -20℃, -80℃, or in liquid nitrogen vapor.

The biorepository includes numerous security and safety features:

  • Redundant back-up systems, dedicated back-up units
  • Around-the-clock automated temperature monitoring
  • In-house HVAC technicians, specializing in cascade refrigeration

Additional specialty lab services

Tissue & Liquid Biopsy

Precision offers a range of complex solutions to analyze tissue and liquid biopsies, including quantitative multiplex immunofluorescence, and our proprietary ApoStream platform which can isolate and enrich circulating tumor cells for downstream analysis.

Bioanalytical Testing

We provide bioanalytical support for biologics, cell therapies, gene therapies, and offer companion diagnostics development services. Our bioanalytical group is recognized for their leadership in immunogenicity testing.

Biospecimens

We stock a range of cryopreserved cells, all of which are ready for immediate domestic and international delivery through our network of distributors. Additionally, we offer prospective collections for any study need.

Discover how we can advance your clinical development program with our comprehensive immune monitoring services.

Discover how we can advance your clinical development program with our comprehensive immune monitoring services.

Explore our other areas of expertise