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Cytokine and Protein Biomarker Assay Services

Detect and quantify a wide range of protein biomarkers to guide critical decisions in your therapeutic programs

Concentration of specific proteins in blood and tissue may help assess immune activity and drug-mediated responses, understand inflammatory response pathways or disease presence and progression, and ultimately guide decision-making in a novel therapeutic program.

To detect and measure these protein biomarkers, immunoassays are widely used in clinical research. At Precision, we develop and customize each immunoassay based on project requirements and factors such as desired sensitivity, the need to multiplex, and available sample volume.

Cytokine and protein analysis delivered via an array of technologies

  • Luminex®

    Luminex is useful when multiplexed measurements at high sensitivity, even in complex matrices, are needed. We generally utilize the Luminex platform in early phase studies profiling cytokines and other analytes.
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  • Olink Proteomics

    High-multiplex quantification of protein biomarkers with minimal clinical sample volume and exceptional sensitivity and specificity
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  • Cytokine

    Meso Scale Discovery (MSD)

    Measuring a range of analytes in complex sample matrices consistently and at high sensitivity, with applications including ADA, NAb, TAb, and PK assays
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  • Quanterix SIMOA®

    Precise quantification of analytes in multiple matrices at sensitivity down to femtomolar (fM) levels, enabling analysis of analytes that may have been previously undetectable
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  • Western blotting

    Providing western blotting via automated platforms to ensure accurate, reproducible results
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  • ELISA

    Services using the gold standard for quantitative antibody-based bioanalysis, with specialization in immunogenicity assay development
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Solutions for any sensitivity or multiplex needs

Luminex

Olink Proteomics

Meso Scale Discovery (MSD)

Quanterix SIMOA

Jess Automated Western Blotting

ELISA

Sensivity

pg/mL

pg/mL

pg/mL

pg/mL

Low pg

ng/mL – pg/mL

Dynamic Range

>4 logs

3-4 logs

>4 logs

>4 logs

3-4 logs

2 logs

Multiplex Capabilities

50-100

45/92

10

4

1-3

1

Sample Volume

50 µL

1 µL

25 µL

10 – 75 µL (25 µL avg.)

3 µL

50 – 100 µL

Use

Early stages

All stages

All stages

All stages

All stages

All stages

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Combine and analyze biomarker and clinical trial data

To help researchers understand and interpret biomarker assay data in the context of other assays and their clinical trial data, Precision provides our proprietary QuartzBio® Translational Informatics platform for managing and analyzing multidimensional data.

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Collaborate with us for a personalized plan

Precision’s scientists take a collaborative approach to projects and can provide recommendations on assay strategies and implementation, if needed. Services can be provided individually or as part of a comprehensive therapeutic development package including biomarker assays and clinical trials.

Build on your research with related specialty lab services

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    Bioanalytical Testing

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