Target Validation, Biomarker Validation, and Safety
Effective validation of therapeutic targets and biomarkers
Precision for Medicine, with a specific focus on histopathology and access to diverse biospecimens, provides a range of human tissue–based research services from the preclinical to clinical stages of development. We specialize in various programs involving small molecule, large molecule, and advanced therapeutics (gene and cell therapies). Our expertise in genomics and cell biology supports you in understanding target expression and localization, determining tumor biology and cellular interplay, and characterizing novel therapeutic entities.
Precision’s technologies providing biomarker and safety insight
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Target Expression
Using a proprietary qRT-PCR-based platform, whole body target expression data supports target validation, drug repurposing, evaluation of potential clinical safety concerns, and validation of animal models. -
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Cell-Based Assays
Developing and qualifying 2D and 3D human in vitro cell-based models, using a broad range of human primary cell types. These models are further utilized in bioassays, with the analysis enabling a variety of endpoints. -
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Fluorescence In Situ Hybridization (FISH)/ISH
Development of multiplex FISH/ISH assays to detect abnormalities in a range of tissues, including hematological and solid organ tumors. -
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Multiplex immunofluorescence (mIF)
Automated multiplex immunofluorescence services that enable quantitative visualization of up to 9 markers in tissue and liquid biopsies. -
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lmmunohistochemistry (IHC)
End-to-end IHC solutions including kitting, sample logistics, staining via all major platforms, and in-house pathology services. -
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Tissue Biospecimens
Thousands of IRB-approved, clinically annotated biospecimens, including samples characterized via next-generation sequencing (NGS), are available to help researchers optimize biomarker and diagnostic development. These are ready to ship the same day to your lab.
Winston-Salem, North Carolina, US
IHC/mIF Stainers & Scanners
- Dako Autostainer Link 48
- Dako PT Link
- Leica Bond II
- Ventana BenchMark ULTRA
- Aperio GT 450
- 3DHISTECH
Certifications- CAP/CLIA
- ISO 9001:2005
Houston, Texas, US
IHC/mIF Stainers & Scanners
- Leica Bond RX
- Akoya Vectra Polaris
- Aperio GT 450
- InForm / HALO AP
- Halo/AI
Certifications- CLIA
- GxP
Royston, UK
IHC/mIF Stainers & Scanners
- Leica Bond RX
- Dako Autostainer + PT Link
- Ventana Discovery ULTRA
- Aperio AT2
- Akoya Vectra Polaris
- InForm / HALO AP
Certifications- GLP
- GCLP
Explore Precision’s other specialty assay areas
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Immune Monitoring
Leverage sophisticated immune monitoring approaches, including flow cytometry, Epiontis ID® immune cell phenotyping, and cytokine profiling, to characterize the immune cells in your samples and understand their impact on patient biology.
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Bioanalytical Testing
At Precision, we understand the complexities of immunogenicity testing and other bioanalytical methods, with a leadership team that continues to shape and inform regulatory guidance.
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Tissue Biopsy Analysis
At Precision for Medicine, we’re committed to delivering gold-standard tissue sourcing, processing, and analysis services.
Discover the Precision blog
Read our blog to gain more insights and discover work that Precision has supported.
Precision Medicine in Pediatrics: Biomarkers and Assay Development
