Stratégies de recrutement des patients

Trouver les bons patients pour votre essai peut s'avérer difficile, en particulier lorsque les populations concernées sont peu nombreuses, comme c'est le cas pour les essais sur les maladies rares.

L'approche holistique de Precision en matière de recrutement de patients s'appuie sur notre portée mondiale, notre vaste réseau de chercheurs spécialisés dans les maladies et les groupes de défense des patients pour élaborer une stratégie visant à faire correspondre le patient à votre essai clinique en fonction des critères de votre étude. Pour les thérapies ciblées, nous utilisons un dépistage basé sur les biomarqueurs pour trouver les patients susceptibles de répondre à votre thérapie, en agissant rapidement et en garantissant la qualité des données grâce à nos services de laboratoire spécialisés en interne.

Étude de cas : recrutement d'une étude mondiale d'histoire naturelle : Comment trouver 200 patients rares

Un commanditaire a choisi Precision pour gérer une étude mondiale sur l'histoire naturelle d'une maladie rénale rare liée au chromosome X. Cette étude avait été recommandée par la FDA en raison du nombre extrêmement limité de données publiées sur cette maladie rare. L'étude avait été recommandée par la FDA en raison du nombre extrêmement limité de données publiées sur cette maladie rare. L'objectif était de caractériser la fonction rénale et le déclin des patients atteints de la maladie avant d'entamer une étude clinique de phase 2/3. L'étude, qui sera menée aux États-Unis, au Canada, en Australie et en Europe, suivra plus de 200 patients pendant environ deux ans.

Le recrutement était de loin le plus grand défi de l'étude, combinant une faible prévalence de la maladie et une population cible primaire - les jeunes hommes - avec des engagements de vie tels que l'école et le travail qui laissaient peu de temps pour participer à un essai qui n'offrait aucun avantage thérapeutique pour les participants et qui nécessiterait de se rendre dans une clinique tous les 3 à 6 mois.

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L'équipe de Precision for Medicine a été fantastique à bien des égards. Je suis très reconnaissant à l'ensemble de l'équipe pour sa réactivité et sa collaboration. Je leur suis très reconnaissant de leur aide.

- Directeur, Biotech de taille moyenne
Je reconnais que les relations entre les sponsors et les fournisseurs d'ORC peuvent être tendues et difficiles, et qu'il s'agit souvent d'un jeu d'accusation ; cela n'a jamais été mon expérience avec ce groupe, car j'ai vraiment eu l'impression qu'il s'agissait d'un partenariat.

- Directeur, petite entreprise de biotechnologie
Notre partenariat avec Precision est un véritable exemple de collaboration entre un sponsor et un CRO.

- Directeur principal, Biotech de taille moyenne
La précision fait partie de notre équipe. Ils ont passé de longues journées à travailler dur pour faire avancer notre étude. Nous apprécions énormément la rapidité avec laquelle ils ont travaillé.

- Senior Manager, Clinical Trials, Midsize Biotech

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has not third author: true, (SizeLimitingPyMap: {main={hs_id=217320686763, hs_child_table_id=0, hs_updated_at=1784229018395, hs_published_at=1784230314171, description=Rachel Piacente is a Clinical Trial Manager at Precision for Medicine with over 15 years of clinical research experience.  She specializes in oncology, hematology, cell and gene therapy, CAR-T, radiopharmaceuticals, and multinational Phase I–IV trials.  Rachel has proven expertise in trial operations, site management, regulatory compliance, budgeting, vendor oversight, and cross-functional team leadership across US and global studies., avatar=Image{width=1010,height=1305,url='https://5014803.fs1.hubspotusercontent-na1.net/hubfs/5014803/Rachel%20Piacente_pic.jpg',altText='Rachel Piacente_pic',fileId=217303397279}, lastname=Piacente, hs_initial_published_at=1784230182153, hs_created_by_user_id=65712240, hs_created_at=1784228917126, hs_is_edited=false, hs_deleted_at=0, name=Rachel, job=Clinical Trial Manager , slug=rachel-piacente, hs_updated_by_user_id=51739740}, second={hs_id=217314606343, hs_child_table_id=0, hs_updated_at=1784229356581, hs_published_at=1784230314171, description=Jennifer Coates is a Project Manager at Precision for Medicine with over a decade of clinical research experience supporting global clinical trials across multiple phases of development and a broad spectrum of therapeutic areas. She specializes in driving the successful execution of theranostic and other complex clinical programs, providing operational leadership to cross-functional teams while ensuring compliance with regulatory requirements and quality standards. Jennifer is known for fostering strong partnerships with sponsors and study teams, enabling collaboration, operational excellence, and the production of high-quality project deliverables., avatar=Image{width=2185,height=3261,url='https://5014803.fs1.hubspotusercontent-na1.net/hubfs/5014803/JenCoates.jpeg',altText='JenCoates',fileId=217308893107}, lastname=Coates, hs_initial_published_at=1784230182153, hs_created_by_user_id=65712240, hs_created_at=1784228926906, hs_is_edited=false, hs_deleted_at=0, name=Jennifer, job=Project Manager, slug=jennifer-coates, hs_updated_by_user_id=51739740}, third={}})

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has third author: false, (SizeLimitingPyMap: {main={hs_id=199521241215, hs_child_table_id=0, hs_updated_at=1774887081250, hs_published_at=1784230314171, description=An industry veteran with nearly three decades of experience in the clinical research industry and deep expertise in clinical operations and strategic leadership across both pharmaceutical and CRO environments. Held pivotal roles as Head of Clinical Operations for Greater China at Boehringer Ingelheim, leading trials in oncology, respiratory, stroke, and cardio-metabolic diseases and CEO of George Clinical, a global CRO with strong scientific capabilities in renal and oncology therapeutic areas. At Precision for Medicine, a leader for business strategy across the Asia Pacific region. Focused on driving regional growth, building strategic partnerships, and supporting excellence in portfolio delivery and client satisfaction. An acknowledged driver of precision-driven solutions that improve patient outcomes., avatar=Image{width=276,height=290,url='https://5014803.fs1.hubspotusercontent-na1.net/hubfs/5014803/James%20Cheong.png',altText='James Cheong',fileId=199519079710}, linkedin=https://www.linkedin.com/in/james-cheong-36a543a/, lastname=Cheong, hs_initial_published_at=1762885727645, hs_created_by_user_id=78347666, hs_created_at=1762885637470, hs_is_edited=false, hs_deleted_at=0, name=James, job=Senior Vice President, Asia Pacific, Clinical Solutions, slug=james-cheong, hs_updated_by_user_id=51739740}, second={hs_id=199519203221, hs_child_table_id=0, hs_updated_at=1770145994248, hs_published_at=1784230314171, description=Highly accomplished global clinical operations executive with nearly three decades of experience providing strategic leadership, regional expansion, and operational excellence across Asia Pacific. Brings deep expertise across clinical development, project and portfolio operations, biometrics, regulatory affairs, safety and pharmacovigilance, quality management, and financial governance. Proven builder and scaler of high‑performing teams and start‑up operations in both regional and global environments. Recognized industry leader who actively contributes to advancing clinical research standards through advisory and governance roles across Asia., avatar=Image{width=276,height=290,url='https://5014803.fs1.hubspotusercontent-na1.net/hubfs/5014803/Jing%20Ping%20Yeo.png',altText='Jing Ping Yeo',fileId=199530854290}, linkedin=https://www.linkedin.com/in/jing-ping-yeo/, lastname=Yeo, PhD , hs_initial_published_at=1762893310168, hs_created_by_user_id=78347666, hs_created_at=1762893091367, hs_is_edited=false, hs_deleted_at=0, name=Jing Ping, job=Vice President, Clinical Operations, Head of Asia Pacific, slug=JingPing-Yeo, hs_updated_by_user_id=51739740}, third={hs_id=199528025104, hs_child_table_id=0, hs_updated_at=1774885968488, hs_published_at=1784230314171, description=With 20+ years of experience in the clinical trial industry, he has led project management, clinical operations, and business development teams. Prior to joining Precision, he served as the General Manager of Emerald (formerly George Clinical) China, and held project management and business development leadership roles at ICON, WuXi CDS, IQVIA, and KUNTUO. He has successfully led teams to complete more than 120 Phase I–IV clinical trials, many of which were MRCT studies across Asia‑Pacific, Australia, and the United States. He holds a Master’s degree in Urology from Peking University First Hospital., avatar=Image{width=276,height=290,url='https://5014803.fs1.hubspotusercontent-na1.net/hubfs/5014803/Zhenfei%20Yin.png',altText='Zhenfei Yin',fileId=199530854553}, lastname=Yin, hs_initial_published_at=1762893310168, hs_created_by_user_id=78347666, hs_created_at=1762893190542, hs_is_edited=false, hs_deleted_at=0, name=Zhenfei, job=China Country Head, Senior Director, Project Management, slug=Zhenfei Yin, hs_updated_by_user_id=51739740}})

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has third author: false, (SizeLimitingPyMap: {main={hs_id=214928090133, hs_child_table_id=0, hs_updated_at=1781285625399, hs_published_at=1784230314171, description=Deborah Spencer is a Senior Director of Project Management at Precision for Medicine with over 25 years of experience in clinical research. She specialises in leading global clinical trials across multiple phases, with deep expertise in complex study delivery. Deborah provides strategic oversight of programmes, leads high-performing teams, and partners closely with sponsors to ensure successful execution and regulatory readiness., avatar=Image{width=1200,height=1200,url='https://5014803.fs1.hubspotusercontent-na1.net/hubfs/5014803/Deborah%20Spencer.jpg',altText='Deborah Spencer',fileId=214838919278}, lastname=Spencer, hs_initial_published_at=1781285742914, hs_created_by_user_id=26433386, hs_created_at=1781285562019, hs_is_edited=false, hs_deleted_at=0, name=Deborah, job=Senior Director, Project Management, slug=deborah-spencer, hs_updated_by_user_id=51739740}, second={hs_id=214928170660, hs_child_table_id=0, hs_updated_at=1781285676367, hs_published_at=1784230314171, description=Anthea Gates is a Project Director with approximately 30 years of drug development and medical device industry expertise across all phases, over a variety of indications including breast, lung cancer, solid tumors and lymphoma, cutaneous T-cell lymphoma, malignant melanoma, squamous cell carcinoma, rare haematologic disease, autoimmune rheumatology, osteoarthritis, ocular burns, liver cirrhosis, myopia and pre-eclampsia.  Committed to delivering quality and passionate about building positive relationships with clients and study teams to promote cohesive business practices and ensure the successful management of projects from start to finish. Anthea holds a proven track record in effective leadership of cross-functional teams across programs of studies, to the accomplishment of operational excellence., avatar=Image{width=372,height=546,url='https://5014803.fs1.hubspotusercontent-na1.net/hubfs/5014803/profile.jpg',altText='profile',fileId=214846873938}, lastname=Gates, hs_initial_published_at=1781285742914, hs_created_by_user_id=26433386, hs_created_at=1781285639221, hs_is_edited=false, hs_deleted_at=0, name=Anthea, job=Project Director, slug=anthea-gates, hs_updated_by_user_id=51739740}, third={hs_id=214928090141, hs_child_table_id=0, hs_updated_at=1781285738567, hs_published_at=1784230314171, description=Claire Delaville is a Senior Project Manager at Precision for Medicine. She brings 18 years of experience across preclinical and clinical research, including more than a decade leading Phase I to IV studies in oncology, rare diseases, and immunology, with direct experience in first-in-human and multicenter oncology trials. Claire is responsible for maintaining study quality through inspection readiness, corrective action planning, and proactive risk mitigation. She also oversees study budgets and vendor performance to support coordinated delivery across functions, drawing on a scientific foundation that includes a PhD in Neurosciences and Neuropharmacology. Based in Paris, France, Claire aligns scientific insight with operational execution to support successful trial outcomes., avatar=Image{width=1200,height=1200,url='https://5014803.fs1.hubspotusercontent-na1.net/hubfs/5014803/Claire%20Delaville.jpg',altText='Claire Delaville',fileId=214838927033}, lastname=Delaville, hs_initial_published_at=1781285742914, hs_created_by_user_id=26433386, hs_created_at=1781285678112, hs_is_edited=false, hs_deleted_at=0, name=Claire, job=Senior Project Manager, slug=claire-delaville, hs_updated_by_user_id=51739740}})