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Services qPCR

Fournissant des informations quantitatives sur des cibles connues d'ADN et d'ARN, la qPCR est l'un des outils de base des études précliniques et cliniques.
Precision propose une suite d'applications qPCR, notamment des essais de génotypage, des essais de variation du nombre de copies et le profilage de l'expression des gènes à l'aide du système QuantStudio™ 12K Flex Real-Time PCR.
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Capacités d'analyse de l'ADN et de l'ARN par qPCR de Precision

Nous pouvons concevoir, valider et mettre en œuvre une large gamme d'essais qPCR, y compris :

  • Génotypage : généralement utilisé pour évaluer un groupe spécifique de gènes lorsque les anomalies sont connues à l'avance.
  • Variation du nombre de copies : utile pour cribler des gènes spécifiques lorsque l'on soupçonne une amplification ou une délétion du gène.
  • Profilage de l'expression génétique : mesure de la différence des niveaux d'expression d'un groupe spécifique de gènes.
  • Analyse des SNP

Nous sommes également spécialisés dans les applications difficiles telles que l'isolement de l'ARN à partir de cellules rares et l'analyse à l'aide de la qRT-PCR (relative ou comparative).

L'instrumentation

Precision utilise l'instrumentation qPCR QuantStudio 12K Flex en conjonction avec la technologie OpenArray™.

OpenArray est une technologie abordable qui minimise l'utilisation de réactifs et équivaut à l'exécution de 32 plaques de 384 puits, générant 12 000 points de données.

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Une portée mondiale, un soutien multisite

Nos services de qPCR prennent en charge la recherche préclinique et clinique, y compris les études multi-sites, menées partout dans le monde.

Travailler avec Precision

Les scientifiques des laboratoires spécialisés de Precision adoptent une approche collaborative et consultative des projets et peuvent fournir des recommandations sur les stratégies et la mise en œuvre des essais de biomarqueurs. Les services peuvent être fournis individuellement ou dans le cadre d'une offre globale de développement thérapeutique comprenant des essais de biomarqueurs et des essais cliniques.

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    Services comprenant le séquençage de l'ARN-seq, le séquençage de l'exome entier et le séquençage ciblé de l'ADN/ARN à l'aide des plateformes NGS d'Illumina et de Thermo-Fisher.
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    NanoString

    Panneaux permettant l'analyse simultanée de 800 gènes ; idéal pour les projets nécessitant une analyse hautement multiplexée, tels que l'oncologie et le développement de thérapies auto-immunes.
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Explorer le blog de Precision

Lisez notre blog pour en savoir plus et découvrir les travaux soutenus par Precision.

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    Rob Maiale
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Translational Research - Biomarkers

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    Deborah P.
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    Christie .
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Read: Optimizing Immunohistochemistry Validation and Regulatory Strategies Optimizing Immunohistochemistry Validation and Regulatory Strategies

Translational Research - Biomarkers - Assays

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    has not third author: true, (SizeLimitingPyMap: {main={hs_id=159488778874, hs_child_table_id=0, hs_updated_at=1714461729999, hs_published_at=1758208109248, description=Kennon Daniels is a scientific and regulatory in vitro diagnostic authority, specializing in the development of US regulatory strategies and FDA marketing submissions for IVD assays and instruments. Her expertise spans all aspects of product development, analytical and clinical trial protocol designs, Q-Submissions, IDEs, de novos, 510(k)s, and pre-market approval platforms., avatar=Image{width=576,height=576,url='https://5014803.fs1.hubspotusercontent-na1.net/hubfs/5014803/PfM%20Website/Headshots/Headshots%20no%20background/Kennon%20Daniels.webp',altText='Kennon Daniels',fileId=165893120790}, linkedin=https://www.linkedin.com/in/kennon-daniels-ph-d-84a90b6, hs_name=, hs_path=, lastname=Daniels, hs_initial_published_at=1758208027822, hs_created_at=1709645745105, hs_is_edited=false, hs_deleted_at=0, name=Kennon, job=, slug=kennon-daniels, email=, hs_updated_by_user_id=13243181}, second={hs_id=182710436924, hs_child_table_id=0, hs_updated_at=1754641257915, hs_published_at=1758208109248, description=Christie Bongel, MS, CT(ASCP), brings nearly two decades of experience in both research and clinical medicine. As the site director for Precision for Medicine’s IHC Center of Excellence in North Carolina, she excels in managing scientific operations and collaborating with clients. Christie is skilled in cytology, laboratory medicine, and molecular diagnostics. Her role focuses on building an energized team dedicated to delivering life-changing outcomes for patients. Christie earned her MS in Applied Biotechnology and is an ASCP certified cytotechnologist., avatar=Image{width=287,height=287,url='https://5014803.fs1.hubspotusercontent-na1.net/hubfs/5014803/PfM%20Website/PfMxMarkentive/authors/Christie-Bongel_Square_260px-1.png',altText='Christie-Bongel_Square_260px-1',fileId=194123799456}, lastname= Bongel, hs_initial_published_at=1731517828480, hs_created_by_user_id=28386183, hs_created_at=1731419696820, hs_is_edited=false, hs_deleted_at=0, name=Christie, job=Site Director - Histology, slug=christie-bongel, hs_updated_by_user_id=13243181}, third={}})
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