Clinical Application: Identification of folate receptor alpha (FRA) positive CTCs for patient stratification Key Words: CTCs, ApoStream®, patient stratification, protein expression, NSCLC Background: This study was initiated to explore the utility of using biomarker expression levels in CTCs as a means of patient selection for treatment in a clinical trial. […]

Clinical Application: Pharmacodynamic analysis of a DNA damaging agent to identify a predictive signature for clinical response Key Words: CTCs, ApoStream®, pharmacodynamics, DNA damage, protein expression, LSC, breast cancer Background: Topoisomerase 1 is a nuclear enzyme that plays an essential role in DNA replication, transcription, recombination, and repair. It is […]