Pathology Services

Precision’s group of highly qualified Board certified Pathologists support all areas of clinical research, including biomarker discovery and evaluation, companion diagnostics development, and in vitro diagnostics development.

Our team can develop special stains for IHC across all major platforms and interrogate large cohorts of samples using custom high-density tissue microarrays (TMA). Tumor assessments can be performed in conjunction with our Multiplex Immunofluorescence services, and microdissection can be performed for RNAseq or NanoString applications. In addition we develop kitting, and our global lab network provides logistics that allow for rapid turnaround of results.

Pathology Services

Precision’s group of highly qualified Board certified Pathologists support all areas of clinical research, including biomarker discovery and evaluation, companion diagnostics development, and in vitro diagnostics development.

Our team can develop special stains for IHC across all major platforms and interrogate large cohorts of samples using custom high-density tissue microarrays (TMA). Tumor assessments can be performed in conjunction with our Multiplex Immunofluorescence services, and microdissection can be performed for RNAseq or NanoString applications. In addition we develop kitting, and our global lab network provides logistics that allow for rapid turnaround of results.

Pathology capabilities

Kitting & logistics

Our team manufactures and ships kits to support the stable transit of tissue samples from anywhere in the world to one of our laboratories:

  • Formalin for fixation and transport
  • FFPE blocks & slides
  • Validated temperature controlled kits for tissues and CTCs

Tissue processing can be a stand-alone service or included as part of a tissue based assay

  • Paraffin Embedding
  • Sectioning
    • Slide mounted for staining
    • Curls for nucleic acid extraction
  • H&E Staining to assess tissue quality
  • Whole slide digital imaging
Expert analysis

We also offer Board certified Pathologist scoring, review, & annotation of tissues and cells.

Integration with other Precision services
  • Special stains for IHC
  • High density tissue microarrays (TMA)
  • Tumor and tissue assessment in conjunction with quantitative multiplex immunofluorescence
  • Microdissection of samples for RNAseq or NanoString analysis
  • Analysis of samples in support of companion diagnostic development
Global reach, multi-site support

Our pathology services support preclinical and clinical research, including multi-site studies, conducted anywhere in the world.

Working with Precision

Precision’s specialty lab scientists take a collaborative and consultative approach to projects and can provide recommendations on biomarker assay strategies and implementation. Services can be provided individually or as part of a comprehensive therapeutic development package including biomarker assays and clinical trials.

Related services

Immunohistochemistry (IHC)

Precision’s IHC services can be customized based on study needs, including logististical and kitting processes, development of special stains, and creation of a custom assay and scoring system.

Multiplex Immunofluorescence

We offer automated multiplex immunofluorescence (mIF) services that enable quantitative visualization of up to 9 markers in tissue and liquid biopsies, and individual cells. mIF can be integrated with other methods including co-analysis using FISH/ISH.

Fluorescence In Situ Hybridization (FISH) / ISH

Detect chromosomal abnormalities and profile gene expression in tissue or liquid biopsies using our multiplex FISH/ISH services. FISH/ISH can be integrated with other technologies to add spatial context and generate multidimensional data sets.

Start the conversation with our experts

Whether you know exactly the type of immune monitoring approach you need or would like expert support with project design, we can deliver.

Start the conversation with our experts

Whether you know exactly the type of immune monitoring approach you need or would like expert support with project design, we can deliver.

Explore other areas of expertise