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Autoimmune Therapeutic Development Services

Autoimmune diseases often present as heterogeneous, with complex disease state biology. Their studies require ongoing monitoring of the immune system.
Precision has a breadth of technologies to monitor the immune system and cell types, and an understanding of when each approach is ideally applicable. In addition Precision supports autoimmune clinical development with an extensive selection of autoimmune biospecimens, along with central lab services for collection, processing, and global logistics of clinical samples.

  • Advanced biomarker capabilities designed to meet the needs of autoimmune studies

  • flowcytometry-icon

    Flow Cytometry

    Standard and spectral flow cytometry, on both research-grade and CLIA-validated instruments
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  • Epiontis ID® Epigenetic Cell Profiling

    Precision’s proprietary immune monitoring technology which delivers robust, repeatable, and cost-effective immune cell phenotyping on any sample type

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  • assays

    ELISpot & Fluorospot

    ELISpot and FluoroSpot - including custom assays in support of gene therapy immunogenicity - from preclinical through clinical development

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  • AdobeStock_208548344
    Cytokine

    Autoimmune Biospecimens

    Inventory of a wide range of indications including tissues, PBMCs, leukopaks are more

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    central-lab-services

    Central Lab Services

    Custom kitting, sample logistics, PBMC processing, and biostorage to meet the complex needs of autoimmune studies
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Precision has expertise in autoimmune disorders and their cellular pathways

Created in collaboration with Nature, this poster maps out the numerous cellular pathways relevant to many autoimmune disorders, as well as common treatments and the cellular targets of those treatments.

Download the poster

Precision’s cell phenotyping technology, Epiontis ID, is ideal for use in autoimmune studies

Epiontis ID has been extensively used for immune monitoring in autoimmune studies across a range of indications, and has validated assays designed for specific autoimmune indications.

Below is data showing the number of studies Epiontis ID has been used for in various autoimmune indications.

IndicationNumber of studiesNumber of samplesStudy phaseStudy yearsSample types

Crohn's Disease

4

9468

Phase 3

2018

Blood

GvHD

5

3411

Phase 3, research

2016, 2017, 2018, 2019

Blood, tissue, PBMC, cells

Psoriasis

6

2834

Phase 1, 2, 4

2015, 2016, 2017, 2018

Blood, tissue

Ulcerative Colitis

2

1575

Phase 2

2015, 2016

Blood, tissue

Asthma

1

1350

Phase 2b

2018

Blood

Lupus

2

1312

Phase 1, 2

2017, 2018

Blood

Behcet's Syndrome

1

672

Phase 4

2015

Blood

Sjorgren's Syndrome

5

479

Phase 1, 2a

2015

Blood, DNA, PBMC

Crohn's, Multiple Sclerosis/ Ulcerative Colitis

2

390

Phase 1

2018

Blood

Rheumatoid Arthritis

2

375

Phase 1b, 2

2014

Blood

Multiple Sclerosis

2

330

Phase 1, 2

2016, 2017

Blood

Celiac Disease

1

204

Preclinical

2016

Blood

Atopic Dermatitis

2

192

Phase 2a, 2b

2018

Blood

Myasthenia Gravis

1

90

Phase 2

2018

DNA

Peanut Allergy

1

31

Preclinical

2017

Blood

IBD

1

30

Preclinical

2017

Tissue

Diabetes

2

20

Research, phase 2

2016, 2017

Blood, cells

NASH

1

48

Phase 1

2018

Blood
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