Maximize the Science of Restraint

Developing a Comprehensive Strategy for Implementing AI & Multi-Omics for Translational Research

Designed for Scientists Who Think Beyond the Assay

Precision for Medicine labs contain the latest omics technologies as well as a few that are proprietary. Our teams are fluent in multiple omics platforms and how they can work together. Because of hard-won insights from thousands of programs, we know which assays deliver, which combinations maximize samples, and which technologies generate signal instead of noise. Clear choices. Disciplined lab execution. Optimized budgets.

2000 translational research programs supported

4M ready-to-ship commercial biospecimens

5 specialty labs providing CLIA-validated and IVDR-compliant assays

Genomics

Interrogate genomic alterations to guide precision development decisions.
Apply genomic profiling to identify somatic and germline variants that inform target validation, patient stratification, resistance mechanisms, and companion diagnostic strategies—enabling confident decision‑making from early translational research through late‑phase clinical development.

Application
- Whole genome and whole exome sequencing
- Single cell genomics
- Amplicon and capture-based enrichment for target characterization
- Minimal residual disease (MRD) detection
- Mutation detection, genotyping
- Vector copy number analysis
- Biodistribution and shedding (gene therapy)
- Liquid biopsy via circulating tumor DNA (ctDNA)
Technologies
- NGS
- ddPCR
- qPCR
- FISH/ISH
- MSK-IMPACT/ACCESS
- CLIA-validated custom NGS assays for patient enrollment
Epigenomics

Capture stable regulatory biology to power robust immune monitoring and stratification.
Deploy bisulfite methylation sequencing to comprehensively measure the methylome and reveal epigenetic regulation underlying cell identity and disease state. Extend insight with Epiontis®, a novel immune monitoring platform using DNA methylation markers uniquely specific to immune cell types, enabling precise, reproducible quantification of immune composition across complex samples and longitudinal studies.

Application
- Epigenetic enabled immune profiling
- Methylation profiling
Technologies
- Epiontis ID
- Bisulfite sequencing
Transcriptomics

Quantify gene expression programs to demonstrate biological response.
Leverage transcriptomic analyses to measure pathway modulation, immune activation, and pharmacodynamic effects across tissues and blood—linking mechanism of action to clinical outcomes and accelerating proof‑of‑mechanism in early‑phase trials.

Application
- Whole transcriptome sequencing
- Gene expression profiling
  
  Transgene expression analysis
- T-cell receptor (TCR) and B-cell receptor (BCR) clonotyping
- Single Cell Transcriptomics
Technologies
- RNASeq
- Single cell RNASeq
- NanoString nCounter
- RT-qPCR
- RT-ddPCR
- RNAScope-ISH
Proteomics

Measure functional protein biology to confirm target engagement and pathway impact.
Utilize proteomic approaches to quantify signaling proteins, cytokines, and biomarker networks that directly reflect drug activity—strengthening translational hypotheses and supporting biomarker‑driven endpoint strategies across development phases.

Application
- Whole transcriptome sequencing
- Gene expression profiling
- Transgene expression analysis
- T-cell receptor (TCR) and B-cell receptor (BCR) clonotyping
- Single Cell Transcriptomics
Technologies
- RNASeq
- Single cell RNASeq
- NanoString nCounter
- RT-qPCR
- RT-ddPCR
- RNAScope-ISH
Cytomics

Define immune cell composition and function with clinical‑grade precision.
Apply flow cytometry and cell‑based immune monitoring assays to characterize immune populations, activation states, and functional responses—enabling clear assessment of pharmacodynamic effects, safety signals, and response biology in immunology‑driven programs.

Application
- Immune phenotyping
- Cell classification
- Pharmacokinetics (PK)
- Pharmacodynamics (PD)
- MRD detection
Technologies
- Flow cytometry (multiplexing)
- Circulating tumor cell isolation (ApoStream)
- ElSpot Assays
Spatialomics

Preserve tissue context to explain response heterogeneity.
Integrate spatially resolved molecular profiling with histopathology to map gene and protein expression within intact tissue architecture—revealing cell‑cell interactions and microenvironmental drivers that inform indication selection and combination strategies.

Application
- Spatially resolved cell classification by gene and protein expression
- Spatial transcriptomics
- Spatial proteomics
Technologies
- mlF
- Akoya Phenolmager HT (up to 8 markers)
- PhenoCycler Fusion (60+ markers)
- Indica Labs
Pathomics

Transform tissue pathology into quantitative, decision‑ready biomarkers.
Apply advanced histopathology and digital pathology analytics to extract objective, scalable features from tissue architecture and biomarker staining—supporting deep biomarker profiling with quantitative measurements for tissue histopathology

Application
- End-to-end digital pathology workflows
- Quantitative Al-powered pathology
- Pre-screening for validated downstream output
- Real-time access to sponsor sample viewing and sharing
Technologies
- Scanner suite
- Tissue processing workflows
- Al algorithms
- PathAI-AISight

Multi Omics and AI with Precision for Medicine

Budgets Matter. You Cannot Afford to Chase Non‑Actionable Data

Streamline your multi‑omic strategy to reduce waste and complexity, so every assay, sample, and dollar delivers value.

Multi‑Omic Analysis, Only What Your Program Needs

Assay strategies designed around discovery, development, and validation goals. No overselling. No unnecessary testing.

Precious Samples from Curated Cohorts in Your Indication

Start confidently with pre‑characterized, ethically sourced biospecimens, ready to ship the same day.

Future‑Proof Alignment for Your Clinical Trial Protocol

Integrated lab and trial capabilities ensure assays perform in real‑world clinical settings, because they are designed with downstream execution in mind.

Download the multi-omics ebook