Clinical Samples in Flow Cytometry: Best Practices for Sample Preparation and Sample Choice

Webinar - On Demand

Clinical Samples in Flow Cytometry: Best Practices for Sample Preparation and Sample Choice

Date: May 2, 2023

Duration: 1 hour

Assessing whole blood sample stability is crucial for developing pharmacodynamic flow cytometry assays, as it impacts the detection of markers and cell populations. Enhanced sample preparation, including the use of fixative-containing tubes or freezing with custom fixatives, can significantly extend stability, making transport from clinical sites feasible. Fixatives may preserve samples for weeks to months, and PBMC isolation offers another high-quality data option.

This webinar will cover strategies to improve sample stability and alternatives to whole blood in flow cytometry, showcasing successful clinical implementations.

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Speakers

Deb Phippard, PhD

Chief Scientific Officer at Precision for Medicine. Pharma industry veteran and expert at biomarker-driven clinical trial design and execution. Leader of biomarker and drug development programs for pharmaceutical and diagnostics companies, as well as the National Institutes of Health. Spearheaded the discovery of pharmacodynamic biomarkers and novel targets for inflammatory disease therapy.

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Angelina Bisconte

Vice President, Translational Biology at Precision for Medicine. Authority in utilizing human primary biological tissue and cells in research and drug discovery. She is a developer of translational biomarkers for Phase I/II clinical programs in autoimmunity, inflammation and cancer, and is an expert in phenotypic cell-based assays.

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