Leukopaks

Research-grade and GMP-grade leukopaks, shipped directly to your lab

Customizable leukopaks from donor selection to delivery – fresh, cryopreserved, and mobilized leukopaks are collected from healthy or disease-state donors in our in-house apheresis center. Precision offers both Research-grade and GMP-grade leukopaks to meet your research applications.

Curated Leukopaks for your research needs

The benefits of Precision leukopaks begin with our CLIA-certified, FDA-registered apheresis collection center, allowing for customization of your product from donor identification to delivery. Donor demographics, HLA type, and phenotype can be selected based on your criteria. Our in-house immunology laboratory allows for custom cellular processing of leukopaks into PBMCs, or other isolated cell lines upon request.

Pre-freeze viability

Available Leukopak products

Leukopak Type	Format	Size/Number of Cells
Research-Grade	Fresh, Cryopreserved Healthy, Disease-state	Quarter pak: 2B total cells Half pak: 4-6B total cells Full pak: 8-12B total cells
Research-Grade, Mobilized	Fresh, Cryopreserved Healthy, Disease-state	Full pak: 20-40 billion total cells; up to 625 million CD34+ stem cells
GMP-Grade	Fresh Healthy	Half pak: 4-6 billion total cells Full pak: 10-12 billion total cells

Choosing the right Leukopak for your research

Fresh Leukopaks

These leukopaks are collected from healthy donors before being shipped fresh for swift use - eliminating the need for freezing or storing them.

Because the cells are shipped fresh, they're used for short-term applications and experiments.

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Benefits
- Get prompt shipments of cells ready for isolation
- Eliminate the need to freeze cells, translating to high viability and functionality
- Preserve specific cell subsets and delicate characteristics
Drawback
- A missed or late shipment could mean losing all viability
- The short timeline can cause logistical challenges and potentially increase costs
Cryopreserved Leukopaks

As the name suggests, cryopreserved leukopaks are frozen at ultra-low temperatures to preserve the sample cells for extended periods of time.

The cryopreservation and thawing processes result in minimal viability loss while providing more flexibility in shipment schedules and experimentation timelines.

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Benefits
- Extend your experimental window by storing samples until you need them
- Improve batch consistency and reproducibility with preserved, standardized cell samples
Drawback
- Freezing and thawing processes can lead to cell loss
- Thawing and recovery time may delay research or application timelines
Mobilized Leukopaks

Mobilized leukopaks are collected from donors who were treated with a drug that stimulates an increased release of stem cells from the bone marrow into circulation.

The increased concentration of stem and progenitor cells in mobilized leukopaks is ideal for cell therapy and research applications.

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Benefits
- Acquire the highest concentration of CD34+ stem cells up to 10x more than in normal leukopaks
- 2-4x more total cell yields than in normal leu
- Enhance reproducibility with a consistent supply of cells from a single donor
Drawback
- Mobilized leukopaks tend to cost more than normal leukopak products, but the benefits outweigh the costs

Leukopaks are collected from our database of deeply characterized donors, providing detailed information

Demographics
Medical history, disease characterization, outcome data, CBC report available, all viral negative and vaccination status captured
Immunophenotyping via flow cytometry
Recallable, HLA- typed donors
Custom donor specifications upon request

Donors undergo an initial screening process prior to their first donation and are then prescreened every 3 months to ensure they meet our donation standards.

High-quality Leukopaks designed for your research
Donor Recallability

Recall donors with your desired characteristics to optimize your results.
Same-Day Delivery

The location of our apheresis center allows for same day delivery to Greater Boston, and next-day delivery across the United States.
Same-Day Processing

Our on-site immunology lab allows for a quick turnaround from collection to processing, ensuring high cell viabilities.
Customizable Product

From donor selection to processing, cell isolations, and shipping—our leukopaks are made to fit your needs.

Precision’s Leukopaks are collected at our in-house Apheresis Center

Located in the Greater Boston Area

Our in-house, CLIA-certified Apheresis Donor Center is fully equipped with the Spectra Optia® Apheresis System and a staff of experienced nurses and scientific experts. We collect leukopaks from healthy and disease-state donors that are customizable from donor to delivery – to meet your research needs.

On-Site Rapid Sample Analysis for Leukopaks

In conjunction with our in-house apheresis center, we have an on-site immunology lab dedicated to rapid analysis and processing of samples.

Immunophenotyping panels via flow cytometry

Purity assessment on isolated cell subsets
Custom panels available

ELISpot/Fluorospot sample analysis

IFN-γ immune responses
Custom assays available

Cell culture

PBMCs, BMMCs, DTCs
T-cell expansion
Enriched cell populations

CBC analysis

5-part differential

ELISA

AV serotype assays
Custom assays available

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PBMC & Sample Processing

Sample processing with expertise in PBMC isolations from labs across 5 continents

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Flow Cytometry

Standard and spectral flow cytometry, on both research-grade and CLIA-validated instruments

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Cell-Based Assays

Developing and qualifying 2D and 3D human in vitro cell-based models using a broad range of human primary cell types, with analysis enabling a variety of endpoints

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