March 24, 2021

An Analysis of the CK2 Pathway in PBMCs, CTCs, and Plasma in Patients with Solid Tumors

Clinical Application: Pharmacodynamic Assessment of a CK2 Inhibitor Key Words: PBMCs, CTCs, plasma, biomarker expression, pharmacodynamics Background: CK2 protein kinase is a constitutively active enzyme that mediates signaling in multiple pathways including oncogene and cytokine signaling. CK2 is an attractive target for anticancer therapy due to its overexpression in most […]
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March 24, 2021

Therapeutic Target Analysis in CTCs Isolated from NSCLC Patients Using ApoStream®

Clinical Application: Identification of folate receptor alpha (FRA) positive CTCs for patient stratification Key Words: CTCs, ApoStream®, patient stratification, protein expression, NSCLC Background: This study was initiated to explore the utility of using biomarker expression levels in CTCs as a means of patient selection for treatment in a clinical trial. […]
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Precision for Medicine is part of the Precision Medicine Group, an integrated team of experts that extends Precision for Medicine’s therapeutic development capabilities beyond approval and into launch strategies, marketing communication, and payer insights. As one company, the Precision Medicine Group helps pharmaceutical and life-sciences clients conquer product development and commercialization challenges in a rapidly evolving environment.

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